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A B S T R A C T S
Results:
The mean age was 64.5 years (SD 7.7, range
50 to 82). Two-third (76%) of patients who were aged 50 to
70 years. More than half of patients were male (64%), received
chemotherapy (64%) and within the first year of cancer
diagnosis (65%). The ECOG PS score was 3 to 4 for less than
half of patients (44%), and CCI score was 2 to 3 for one-third
of them (29%). The reported highest level of QoL was cognitive
functioning (mean 86.4, SD 20.3), while the worst QoL was role
functioning (mean 63.6, SD 24.7). Coughing (mean 43, SD 25)
was the worst symptom followed by insomnia (mean 34.6,
SD 28.7), financial difficulties (mean 34, SD 28) and fatigue
(mean 32.8, SD 23.6). Patients who had low ECOG PS score (
2)
reported statistically significant lower levels of QoL in all of
the functional scales and global health status as well as higher
level of symptom scales as measured by EORTC-C30 and QLQ-
LC13 than those with high ECOG PS score (0–1) (p < 0.05). In
addition, patients who were IADL dependent (IADL score <8)
had statistically significant lower levels of QoL in all of the
functional scales and global health status as well as high level
of symptom scales than those who were IADL independent
(IADL score
<8) (p < 0.01). Physical and daily living needs
(mean 38.0, SD 20.9) and psychological needs (mean 34.6, SD
20.7) were the most common domains of unmet needs. There
were statistically significant negative relationships between
psychological needs and all of the functional scales and
global health status of QoL (r = –0.351 to –0.661, p < 0.001), and
physical and daily living needs and all of the functional scales
and global health status of QoL (r = –0.376 to –0.645, p < 0.001)
Conclusion:
Our results suggest that role functioning
and coughing and insomnia are common QoL issue and
symptoms, and physical/daily living needs and psychological
needs are common domains of unmet needs in older patients
with lung cancer. The levels of QoL in various domains are
related with functional status and unmet needs of patients.
References:
[1] Baker, F., Denniston, M., Haffer, S. C., & Liberatos, P. Change
in health-related quality of life of newly diagnosed
cancer patients, cancer survivors, and controls. Cancer
2009;115(13):3024-3033. doi: 10.1002/cncr.24330
[2] Li, J., & Girgis, A. Supportive care needs: are patients with
lung cancer a neglected population? Psycho-Oncology
2006;15(6):509-516.
Disclosure of Interest:
None declared
Keywords:
Functional status, lung cancer, quality of life,
supportive care needs
P144
DIALOG TASK FORCE FOR DEFINITION OF A GERIATRIC
MINIMUM DATA SET FOR CLINICAL ONCOLOGY RESEARCH
E. Paillaud
1,2,
*, P. Caillet
3
, T. Cudennec
4
, F. Pamoukdjian
5
,
V. Fossey-Diaz
6
, E. Liuu
7
, G. Albrand
8
, R. Boulahssess
9
,
A. L. Couderc
10
, C. Mertens
11
, F. Retornaz
12
, L. Balardy
13
,
F. Rollot-Trad
14
, L. De Decker
15
, T. Aparicio
16
, C. Terret
17
,
H. Le Caer
18
, E. Carola
19
, H. Cure
20
, S. Culine
21
, L. Mourey
22
,
E. Brain
23
, P. Soubeyran
24
and DIALOG
1
Unité de Coordination en OncoGeriatrie Paris Sud, APHP,
2
Departement de Médecine interne et Gériatrie,
3
Unité de
Coordination en OncoGeriatrie Paris Sud, Groupe Hospitalier
Mondor, Creteil,
4
Unité de Coordination en Oncogériatrie Paris
Ouest, Geriatric Department, Ambroise Paré Hospital, APHP,
Boulogne Billancourt,
5
Unité de Coordination en Oncogériatrie
Paris Saint-Denis, Geriatric Department, Avicenne Hospital, APHP,
Bobigny,
6
Unité de Coordination en Oncogériatrie Paris Nord,
Geriatric department, Bretonneau hospital, APHP, Paris,
7
Unité
de Coordination en Oncogériatrie Poitou-Charentes, Geriatric
department, Poitiers University Hospital (CHU), Poitiers,
8
Unité
de Coordination en Oncogériatrie Rhône-Auvergne-Guyane,
Geriatric department, Lyon Civil Hospices, Antoine Charial
Hospital, Francheville,
9
Unité de Coordination en Oncogériatrie
PACA EST, Department of Gerontology, Nice University Hospital
(CHU), Cimiez Hospital, Nice,
10
Internal Medicine, Geriatric and
Therapeutic Unit, Sainte Marguerite Hospital (CHU), Marseille,
11
Unité de Coordination en Oncogériatrie Aquitaine, Department
of Clinical Gerontology, Bordeaux Universitary Hospital (CHU),
Bordeaux,
12
Pôle Gériatrique, Centre gérontologique départemental,
Marseille,
13
Unité de Coordination en Oncogériatrie Midi-Pyrenées,
Department of Internal Medicine and Clinical Gerontology, Centre
Hospitalier Universitaire Purpan-Casselardit, Toulouse,
14
Unité
de coordination en Oncogeriatrie Paris Ouest, Institut Curie,
Paris,
15
Unité de coordination en Oncogeriatrie Pays de la Loire,
Department of Geriatrics, Nantes University hospital, Nantes,
16
Gastroenterology and Digestive Oncology Department, Avicenne
Hospital, APHP, Bobigny,
17
Unité de Coordination en Oncogériatrie
Rhône-Auvergne-Guyane, Department of Medical Oncology, Centre
Léon Bérard, Lyon,
18
Service de Pneumologie, Centre Hospitalier de
Draguignan, Draguignan,
19
Unité de Coordination en Oncogériatrie
Picardie, Department of Medical Oncology, GH public du sud
de l’Oise, Creil-Senlis,
20
Unité de Coordination en Oncogériatrie
Rhone-Alpes Annecy-Grenoble, Department of Medical Oncology,
Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble,
21
Unité
de Coordination en Oncogériatrie Paris Nord, Department of
Medical Oncology, Saint-Louis hospital, AP-HP, Paris,
22
Department
of oncology, Institut Claudias Regaud, Toulouse,
23
Department
of Medical Oncology, Institu Curie Hopital Rene Huguenin,
Saint Cloud,
24
Unité de coordination en Oncogeriatrie Aquitaine,
department of Medical Oncology, Institut Bergonié, Bordeaux,
France
Introduction:
The evidence-based added value of geriatric
assessment (GA) in clinical oncology remains poor, partly
due to limited specific clinical research and lack of data
homogenization. A minimum set of geriatric data at baseline
would allow comparing results across reports. Both the Unités
de Coordination en Oncogériatrie (under the umbrella of the
French Society of Geriatric Oncology) and the Unicancer
GERICO cooperative group (dedicated to clinical research in
geriatric oncology) joined their efforts into an intergroup
called DIALOG. DIALOG launched a task force in order to
develop a consensual geriatric minimum data set (MDS) for
research purposes.
Objectives:
To reach a consensus on a minimum set of
geriatric data to be incorporated in clinical trials covering
the elderly cancer population and allowing stratification
according to geriatric risk profile.
Methods:
Following an adapted formal consensus
method, a panel of 7 pairs of geriatricians from 14 geriatric