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[2] Wildiers H, Heeren P, Puts M, Topinkova E, JanssenHeijnen
ML, Extermann M, et al. Internacional Society of Geriatric
Oncology Consensus on Geriatirc Assessment in Older
Patients With Cancer. J Clin Oncol 2014;32(24):2595-603.
[3] Guigoz Y. The Mini-Nutritional Assessment (MNA
®
) Review
of the Literature - What does it tell us? J Nutr Health Aging
2006; 10:466-487.
[4] Kaiser MJ, Bauer JM, Ramsch C, et al. Validation of the Mini
Nutritional Assessment Short-Form (MNA
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-SF): A practical
tool for identification of nutritional status. J Nutr Health
Aging 2009; 13:782-788.
Disclosure of interest:
None declared
Keywords:
Cancer, comprehensive geriatric assessment,
early mortality, short-term outcome
P110
VALUE OF GERIATRIC SCREENING AND ASSESSMENT
IN PREDICTING POSTOPERATIVE COMPLICATIONS IN
PATIENTS OLDER THAN 70 YEARS UNDERGOING SURGERY
FOR COLORECTAL CANCER
K. Fagard
1,
*, J. Casaer
2
, A. Wolthuis
3
, J. Flamaing
4
, K. Milisen
5
,
J.-P. Lobelle
6
, H. Wildiers
7
, C. Kenis
8
1
Department of Geriatric Medicine, University Hospitals Leuven,
2
Faculty of Medicine, KU Leuven,
3
Department of Abdominal
Surgery, University Hospitals Leuven,
4
Department of Geriatric
Medicine, Department of Clinical and Experimental Medicine,
University Hospitals Leuven, KU Leuven,
5
Department of Geriatric
Medicine, Department of Public Health and Primary Care,
University Hospitals Leuven, Academic Centre for Nursing and
Midwifery KU Leuven, Leuven,
6
Consultant in Statistics, University
Hospitals Leuven, Beernem,
7
Department of General Medical
Oncology, Department of Oncology, University Hospitals Leuven, KU
Leuven,
8
Department of General Medical Oncology, Department of
Geriatric Medicine, University Hospitals Leuven, Leuven, Belgium
Introduction:
Nowadays there is a growing consensus that
it is important to assess frailty in older patients undergoing
surgery.
Objectives:
To examine the association between the results
of geriatric screening and geriatric assessment (GA) and the
risk of 30-day postoperative complications in older patients
undergoing surgery for colorectal cancer (CRC).
Methods:
Patients
70 years old, operated on for CRC, were
identified from a prospectively collected database (2009-2015).
All patients underwent screening with 2 geriatric screening
tools (G8 and the Flemish version of the Triage Risk Screening
Tool). The G8-positive patients (scoring
14/17) received
a GA, including living situation, activities of daily living
(ADL), instrumental activities of daily living (IADL), falls,
fatigue, cognition, depression, nutrition, comorbidities and
polypharmacy. Postoperative complications that occurred
within 30 days of surgery were retrospectively collected from
the medical records and classified into severity grades by
the Clavien-Dindo grading system. The primary endpoint is
the occurrence of Clavien-Dindo grade II and above compli-
cations. Logistic regression analyses were used for identifying
predictive variables for complications Clavien Dindo
grade
II.
Results:
One hundred ninety patients (mean = 78 y.), were
included, of whom 115 G8-positive patients received a GA.The
30-day morbidity rate was 50%, 83.0% of the complications
were Clavien-Dindo
II, and 3 patients died. In univariate
logistic regressions on 190 patients, the following variables
were associated with Clavien-Dindo
II complications with
p(wald)<0.05: age, type of tumor, surgical approach, type of
surgery, ECOG-PS score and G8. In the 115 G8 frail patients,
ADL was the only predictive significant (p<0.05) GA variable.
In multivariable logistic regression analysis, age and surgical
approach were independent predictors of Clavien-Dindo
II
complications in the whole group, while ADL was the only
predictor in the G8 frail group.
Conclusion:
Our findings suggest that geriatric screening
and assessment can be of added value to identify an increased
risk of complications after surgery for colorectal cancer in
older patients.
Disclosure of interest:
None declared
Keywords:
Colorectal cancer, elderly, geriatric assessment,
geriatric screening, postoperative complications
P111
FRAILTY AND SURVIVAL IN OLD PATIENTS WITH CANCER;
CLINICAL JUDGMENT AND SYSTEMATIC GERIATRIC
ASSESSMENTS
L. Kirkhus
1,
*, J. Šaltyte Benth
1,2,3
, S. Rostoft
4
, B. H. Grønberg
5,6
,
M. J. Hjermstad
7,8
, G. Selbæk
1,9
, T. Bruun Wyller
3,4
,
M. Harneshaug
1
, M. S. Jordhøy
3,10
1
The Centre for Old Age Psychiatry Research, Innlandet Hospital
Trust, Hamar,
2
HØKH Research Centre, Akershus University
Hospital,
3
Institute of Clinical Medicine, Faculty of Medicine,
University of Oslo,
4
Department of Geriatric Medicine, Oslo
University Hospital, Oslo,
5
The Cancer Clinic, St. Olavs Hospital -
Trondheim University Hospital,
6
Department of Cancer Research
and Molecular Medicine, NTNU, Norwegian University of Science
and Technology, Trondheim,
7
Regional Advisory Unit for Palliative
Care, Department of Oncology, Oslo University Hospital, Oslo,
8
European Palliative Care Research Centre, Department of Cancer
Research and Molecular Medicine, NTNU, Norwegian University of
Science and Technology, Trondheim,
9
Norwegian Advisory Unit on
Ageing and Health, Vestfold Hospital Trust, Tønsberg,
10
The Cancer
Unit, Innlandet Hospital Trust, Hamar, Norway
Introduction:
Assessing frailty in older cancer patients and
thereby estimating an individual’s vulnerability to changes
in health status is highly relevant for planning of treatment.
Many oncologists are not familiar with the concept and do not
assess frailty in their patients.
Objectives:
To compare the oncologists’ categorization of
frailty based on their clinical judgment with a systematic
frailty categorization based on amodified geriatric assessment
(mGA). To investigate if any of these frailty categorizations
were associated with reduced overall survival (OS).