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S98
A B S T R A C T S
The GA included a wide variety of validated tools that
evaluate functional, mobility, cognitive, nutritional, co-
morbidity, polypharmacy, and psychosocial domains.
All patients had also additional questions and physical
measurements to be classified according to Fried frailty
criteria, PACE and Balducci-criteria.
Results:
The study sample comprised 94 elective patients
(35 were female and 59 were male) with histologically
confirmed colon cancer (43.6%) and rectal cancer (56.4%). The
median age was 83 (70-93) years.The clinical cancer stage was
localized in 63.8%, locally advanced in 24.5% and with distant
metastasis in 11.7% of patients. Three patients were classified
as American Society of Anesthesiologists (ASA) 1, 66 patients
as ASA 2 and 24 patients as ASA 3.
All patients were discharge home and the median length
of postoperative stay was 8 (3-148) days. There were three
readmissions, all within 30-day assessment period. The
30-day mortality was 6.4%. The 30-day morbidity was 48%
(including 29.8% major morbidities).
The prevalence of frailty as diagnosed by the Fried, CDM,
PACE and Balducii-criteria were 34%, 50%, 46.8% and 69.1%,
respectively. The results of the univariate and multivariate
logistic regression analysis showed that the frailty status
diagnosed based on CDM, PACE and Fried frailty criteria turned
to be independent risk factors of 30-day mortality (Odds Ratio:
2.84 (1.2-8.3) p=0.04; 1.3 (1.1-2.2) p=0.04; 2.63 (1.1-6.1) p=0.02,
respectively) and of overall postoperative complications (Odds
Ratio: 3.56 (1.4-11.2) p=0.02; 1.4 (1.1-2.5) p=0.03; 2.3 (1.3-1.7)
p=0.01;
1.5 (0.5-4.7) p=0.46) adjusted by age, sex and stage of
the cancer. Balducci frailty criteria did not reached statistical
significance, predicting 30-day mortality and morbidity (OR
1.1 (0.4-2.6) p=0.87; 1.5 (0.5-4.7) p=0.46, respectively). It was not
possible to build a model for the major complications because
of an insufficient number of patients in this subgroup (major
complications were observed only among frail patients).
Conclusion:
Among four studied frailty models, the
Cumulative Deficit Model based on Geriatric Assessment
has the highest predictive possibility of 30-day postoperative
mortality and morbidity in patients with colorectal cancer
qualified for an elective surgery under general anaesthesia.
Disclosure of interest:
None declared
Keywords:
Colorectal cancer, frailty, geriatric assessment,
surgery
P105
IMPLEMENTATION OF THE G8 SCREENING TOOLS IN A
PUBLIC HOSPITAL IN FRENCH GUIANA
J.-L. Joachim
1
, E. Basset
1
, S. Briolant
2
, B. Cenciu
1
, P. Couppié
1
,
J.-P. Droz
3,4,
*
1
Medicine,
2
Geriatrics, Cayenne Hospital,
3
Oncoguyane Cancer
Network, Cayenne, French Guiana,
4
Environment and Cancer
Research Unit, Centre Léon-Bérard, Lyon, France
Introduction:
Frailty screening has been implemented by
the French Cancer Institute. A question was its application in
overseas territories characterized by multiculturality.
Objectives:
To evaluate the feasibility of frailty screening by
G8 tool in elderly cancer patients and possible limits.
Methods:
A prospective 8 months survey of cancer patients
aged
70 years who were scheduled to receive G8 screening.
In patients with G8 < 15/17, a simplified geriatric evaluation
(SGE) was proposed. The G8 tool was administered by a
trained nurse of the outpatient clinic. The SGE was performed
by a geriatrician.
Results:
From 01/09/2015 to 30/04/2016, 130 patients
70 years were followed for cancer in the outpatient clinic, 60
patients (46%) had a G8 screening of which 57 were abnormal.
One patient refused to participate. Six patients have died of
cancer progression. Eleven patients had SGE, 3 had further
follow-up. Patients characteristics: there were 30 men and 30
women; median age was 76 years (extremes: 70–90); cancer
types were: lung (10), hemopathies (9), breast (8), colorectal
(8), (5), unknown (5), gastric (4), anus (3), uterus (2), prostate (2),
and ovary, esophagus, liver, pancreas, one each.
The small number of G8 procedures was due to
organizational problems (only one trained nurse). But there
were also difficulties to obtain all the G8 items: loss of
appetite was biased by the treatment; weight loss during
the last 3 months was difficult to measure in these patients
who don’t follow their weight; number of medications did
not take in account traditional medicine intakes; in these
patients “feeling of their health status” was biased by cultural
perception of health, of disease and of cancer, by belief and by
comparison to their previous heath status.
Conclusion:
G8 screening requires sufficient trained
health professionals and good organization. It is difficult to
apply in the setting of little medicalized and few educated
populations. it may be impacted by the cultural perception of
heath and illness. All these limits are found in tropical areas
and in intermediate and low incomes countries.
Disclosure of interest:
None declared
Keywords:
G8 tool, implementation, tropical area
P106
FUNCTIONAL DEPENDANCY IS PREDICTIVE FOR
NUTRITIONAL STATUS IN ELDERY PATIENTS WITH
HEMATOLOGIC MALIGNANCIES
J. Hajder
1,
*, N. Stanisavljevic
1
, D. Marisavljevic
1,2
, O. Markovic
1,3
,
R. Zivkovic
1
1
Hematology, KBC Bezanijska kosa, Belgrade, Serbia,
2
Hematology,
Medical faculty,
3
Hematology, Medical faculty, Belgrade, Serbia
Introduction:
Malnutrition is common in population older
than 65. The Mini Nutritional Assessment (MNA) short-
form is both a screening and assessment tool which has
been validated for determination of nutritional
status.Toevaluate the prevalence of malnutrition using MNA short-
form in elderly patients with newly diagnosed hematologic
malignancies and its association to functional activity.
Objectives:
To evaluate the prevalence of malnutrition
using MNA short-form in elderly patients with newly diag-