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S96

A B S T R A C T S

pathologies. These include neoplasms in patients over 65

that account for 60% of new cancer cases and 70% of related

deaths in Western Europe and the United States.

Geriatric Oncology is a discipline that embraces 3 key

aspects of our demographic and health needs: the ageing of

the population, the rising incidence of cancer in older patients

and the complexity of cancer management in the elderly.

Objectives:

A retrospective assessment of the results

obtained in the first year after the implementation of a

Geriatric Oncology Unit (June 2014 to October 2015).

Methods:

The model of Geriatric Oncology at Fundació

Althaia is one of integration that includes the collaboration of

a physician in internal medicine specially trained in geriatrics

in the committees for tumours .

Patients over 80 years are assessed in a specific consulting

room (within 4 days), where they undergo a comprehensive

geriatric assessment (CGA). Depending on the CGA results,

patients are assigned to one of the following 4 groups:

Type 1: Competent, “fit” for oncospecific treatment.

Candidates for standard treatment.

Type 2: Vulnerable. Candidates for oncospecific treatment

with geriatric intervention.

Type 3: Fragile. Candidates for tailor-made treatment.

Type 4: Terminal. Candidate for symptomatic treatment.

Results:

Assessment of the results of the oncogeriatric

intervention in patients from the committee for urological

tumours. Twenty-three patients were assessed, 15 of which

presented infiltrating gallbladder tumours (13 stage T2-

4N0M0, 2 BCG refractory in situ carcinoma), 4 prostate

neoplasms (located tumour-high risk, candidates for radical

RT), 4 renal tumours (stage T3 N0-1 M0-1, candidates for

radical nephrectomy) . All patients were candidates for radical

treatment. Mean age was 79.7 years. The classification after

CGA was: 47.8% of patients fit, 17.4% vulnerable, 26.1% fragile

and 8.7% terminal illness. Treatment plan was not changed

pre- or post- CGA in 43.4% of patients. However, intensity of

treatment was adjusted in 56.6%.

Conclusion:

The introduction of a geriatric oncology

assessment in committees for tumours has lead to an

improvement in the selection of patients over the age of 80

candidates for radical surgical treatment.

Disclosure of interest:

None declared

Keywords:

Geriatric assessment

P102

TRANS SECTORAL CARE OF GERIATRIC CANCER PATIENTS

BASED ON COMPREHENSIVE GERIATRIC ASSESSMENT AND

PATIENT-REPORTED QUALITY OF LIFE

H. Schmidt

1,

*, S. Boese

1

, K. Lampe

2

, K. Jordan

3

, E. Fiedler

4

,

U. Mueller-Werdan

5

, D. Vordermark

2

1

Institute of Health and Nursing Sciences, Martin Luther University

Halle-Wittenberg,

2

Department of Radiation Oncology,

3

Department

of Hematology and Oncology,

4

Department of Dermatology,

University Hospital Halle Saale, Halle (Saale),

5

Protestant Geriatric

Centre, Charite - Universitätsmedizin Berlin, Berlin, Germany

Introduction:

For elderly cancer patients the maintenance

of independence, functionality and health related quality

of life (HRQOL) is of great importance. Treatment decisions

and transsectoral care are often complicated by the number

and severity of comorbidities reduced physical and cognitive

functioning and the organization of care at home. Therefore,

the identification of relevant risk factors by comprehensive

geriatric assessment (CGA) is recommended prior to cancer

specific therapy.

Objectives:

Aiming to maintain HRQOL of geriatric cancer

patients we developed an interdisciplinary care program based

on comprehensive geriatric assessment (CGA) and patient

reported HRQOL comprising tailored supportive measures and

telephone based counselling during 6 months aftercare.

Methods:

Pilot testing of the intervention took place in

three centres at the University Hospital Halle Saale to examine

feasibility, acceptance and potential benefit. Oncologic

patients

70 years with at least one comorbidity and/or one

functional impairment, receiving curative or palliative care

were eligible. Primary endpoint is HRQOL (EORTC QLQ-C30,

ELD14), measured at admission and 6 month-follow-up.

Secondary endpoints are symptom burden, unscheduled

readmissions and overall survival.

Results:

Out of n=226 eligible patients n=100 participated

(44%), mean age: 76.3 years (SD 4.8), 47% female. On average

participants had 5 comorbidities (SD 2.8, min. 0, max. 15)

and took 8 medications (SD 3.6, min. 0, max. 15). Follow-up

will be completed by July 2016. Individualized supportive

care was triggered by summarized individual results that

were presented to the treating physicians (e.g. malnutrition,

reduced HRQOL, reduced physical functioning, high

symptom-intensity and depression). Preliminary analyses for

the primary endpoint global HRQOL (n=46) showed clinical

relevant improvement of HRQOL (

10 pts.) for 35%, no change

for 41% and worsening for 24%. Concurrent with worsening of

global HRQOL we found a deterioration of physical function,

mobility and fatigue (EORTC QLQ C30). Comparisons of

professional and patients’ self-assessments including HRQOL

and subgroup analyses describing correlations of risk profiles

with HRQOL and survival will be presented.

Conclusion:

First results show feasibility and potential use-

fulness of the combination of CGA and HRQOL to complement

standard assessments and to decide on individualized

therapeutic measures. The nurse led telephone based after-

care was well accepted.

Disclosure of interest:

H. Schmidt: None declared, S. Boese:

None declared, K. Lampe: None declared, K. Jordan Consultant