Table of Contents Table of Contents
Previous Page  90 / 154 Next Page
Information
Show Menu
Previous Page 90 / 154 Next Page
Page Background

S60

A B S T R A C T S

reaching prolonged remissions. The days of admissions

adjusted to the CIRS scale give us an interesting tool in

order to help physicians to discriminate patients with DLBCL

that will have prolonged admissions when treated with the

standard of care.The CIRS scale also help separate two distinct

OS curves, giving physicians a new tool to help discriminate

worse prognostic patients, making them good candidates for

adapted therapies.

Disclosure of interest:

None declared

Keywords:

Geriatric assessment, lymphoma

P041

COMPREHENSIVE GERIATRIC ASSESSMENT MAY BE USEFUL

ITEM AS PREDICTIVE INDEX OF TREATMENT COMPLETION

FOR ELDERLY PATIENTS WITH LYMPHOMA

M. Shibata

1,

*

1

Internal medicine, Kawanishi, Japan

Introduction:

In the treatment for B-cell lymphoma, a

lot of reports tell us that standard CHOP-like regimen and

rituximab shows good survival. However, the chemotherapy is

difficult for elderly patients to complete, because it has severe

adverse effects. In this point of view, if we can find the index

for the assessment about tolerance in chemotherapy for

elderly patients with malignant lymphoma (ML), patients can

accomplish their treatment without severe adverse effects.

Objectives:

In this report, we investigated the total

conditions of elderly patientswithML throughComprehensive

geriatric Assessment (CGA). Moreover, we examined whether

our assessment is predictive or not for the patients who is

treated with chemotherapy.

Methods:

In this report, we examined 21 elderly patients

who are newly diagnosed as having ML from Apr 2012 to Dec

2014. We adopted CGA as a measurement of elderly patients.

The items in CGA are Barthel Index, geriatric depression scale

(GDS-5), Hasegawa dementia scale for revised, vitality index

(VI).

Results:

In our assessment, 15 patients accomplished the

treatment and in the others the treatment was discontinued

because of their frailty. Twelve of all patients had disease of

advanced stage (stage III or IV), and 6 patients of them have

accomplished their treatment. In patients with advanced

lymphoma, our CGA showed that the 6 patients who

accomplished the treatment have better GDS-5 than the

others (median 4 vs 3 p=0.0198). We did not find difference in

VI, BI or Hasegawa dementia scale, and other hematological

and non-hematological events among the patients.

Conclusion:

CGA may be a useful item as a predictive index

of treatment completion for elderly patients with ML.

Disclosure of interest:

None declared

Keywords:

Comprehensive geriatric assessment, lymphoma

Fig. 2 (abstract P040) – OS and PFS of all series.

Fig. 3 (abstract P040) – OS curve according to CIRS groups.